The research objective was carrying out compara-tive characteristic of reactions of tissues of eye to differ-ent types of implants in intraocular prosthetics in dogs for that purpose a series of experiments in dogs and white mice was carried out. The main objectives of the research was studying the reactions of soft tissues of abdominal wall of white mice to different types of intra-ocular implants with subsequent histological research, and also the research of the reactions of tissues of eye-ball to different types of intraocular implants in dogs by means of the analysis of clinical indicators. For studying the reaction of tissues of white mice to different types of intraocular implants experiment No. 1 was made: as the object of the research white laboratory mice numbering 12 heads, at the age of seven months served. For stud-ying the reactions of tissues of eyeball to different types of intraocular implants in dogs experiment No. 2 was made, the objects of the research were dogs (6 heads), at the age of 6 years, the live mass of animals averaged to 8 kg. During the research it was revealed that at the introduction of the fragment of intraocular implants to white mice the reaction of soft tissue to silicone implants of Acrivet and Dioptrix was characterized by slightly expressed inflammation in the form of inflammatory hyperemia, thus inflammatory hypostasis and leukocyte infiltration were missing. The reaction of tissues to the fragment of intraocular implant from Teflon was charac-terized by expressed inflammation signs. At the implan-tation of silicone intraocular implants of Dioptrix and Acrivet after eyeball evistseration in dogs signs of ex-pressed inflammatory reaction and rejection of fibrous cover were missing, full healing was observed within 7 days after the operation. The application of modified intraocular implant from medical Teflon was followed by the development of acute serous and inflammatory re-action of tissues, the signs of rejection of fibrous cover and slow healing within 30 days after the administration of the animals to additional course of treatment.
intraocular prosthetics, intraocular im-plant, dog, eyeball eversion, eye diseases
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