Two-cluster model trёhkompartmentnye tremor in Parkinson´s disease

E. Maystrenko; S. Tretyakov; D. Dayanova; Nikolay A. Chernikov

doi:doi:10.12737/10863

Two-cluster model trёhkompartmentnye tremor in Parkinson´s disease

Published в Complexity. Mind. Postnonclassic · Volume 4, Issue 1, 2015 · Pages 39–47 · Rubrics: Section the Third paradigm in medical cybernetics

DOI 10.12737/10863

Received: 23.04.2015 Accepted: 23.04.2015 Published: 23.04.2015 Language of publication: RUS

Authors

E. Maystrenko · S. Tretyakov · D. Dayanova · Nikolay A. Chernikov ⁴

4 Emperor Alexander I St. Petersburg State Transport University (Professor)
Russian Federation

ABSTRACT

The scope of compartment-cluster theory of biosystems is in modeling of voluntariness (or involuntariness) of postural tremor and occurs due to the changes in external control drives Ud from 1st (supervisor) cluster. In this case, there are variations in the frequency response and autocorrelation functions, which is typical for tremorogramm of postural tremor and in case of Parkinson´s disease. The voluntariness of the tremor may occur only in the change of quasiattractors’ parameters in models (changing dissipation coefficient b), that is observed in changes of phy-siological states in the organism (con sciously).

KEYWORDS

tremor attractor Parkinson´s disease

Information Text References

Authors:

4. Emperor Alexander I St. Petersburg State Transport University (Professor)

Russian Federation

Type:

Article

Pages:

from 39 to 47

Status:

Published

Language:

Russian

Keywords:

tremor, attractor, Parkinson´s disease

Text

Болезнь Паркинсона – это заболевание, которое связанно с постепенной гибелью определенных нервных клеток, нейронов, которые вырабатывают медиатор дофамин. Из-за этого в организме человека происходит нарушение регуляции уровня возбуждения в стриа-паллидарном комплексе и как итог – наблюдается нарушение параметров движений и мышечного тонуса. Это имеет характерные проявления в виде тремора (дрожи), общей скованности и нарушения позы и всего качества движений. Для описания таких патологий мы предлагаем двухкластерные трёхкомпартментные модели в виде систем дифференциальных уравнений.

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