Stavropol', Stavropol, Russian Federation
Russian Federation
Russian Federation
LLC «AG «Aspect» (Veterinarian)
LLC «RDE «Astrapharm» (Leading veterinarian)
LLC «BioFeron» (Leading veterinarian)
employee
Russian Federation
LLC «RDE «Astrapharm» (Chief science specialist)
LLC «BioFeron» (Chief science specialist)
employee
Russian Federation
06.02.00
68.41
The effectiveness of a new anthelmintic drug for dogs and cats Supramil® tablets was studied. Therapeutic efficacy of the drug Supramil® tablets after a single application of spontaneously infested intestinal nematodes and / or cestodes to dogs and puppies at a dose of 2.5 mg / kg for R-praziquantel and 0.5 mg / kg for milbemycin oxime was 100%. Therapeutic efficacy of the drug Supramil® tablets after a single application of spontaneously infested intestinal nematodes and / or cestodes to cats and kittens at a dose of 2.5 mg / kg for R-praziquantel and 2.0 mg / kg for milbemycin oxime was 100%. Thus, Supramil® tablets are a highly effective treatment for the most common intestinal helminthiases of dogs and cats.
efficacy, Supramil® tablets, R-praziquantel, milbemycin oxime, dogs, puppies, cats, kittens, intestinal nematodes, intestinal cestodes, mixed invasion
1. Arakel'yan, P.C. Epidemiologo-epizootologicheskie osobennosti dirofilyarioza na territorii Astrahanskoy oblasti: spec. 03.00.19 «Parazitologiya»: avtoref. dis. … kand. med. nauk / P.C. Arakel'yan. - M., 2007. - 25 s.
2. Arhipov, I.A. Veterinarno-sanitarnye i medicinskie problemy, obuslovlennye povysheniem chislennosti sobak i koshek v gorodah. / I.A. Arhipov, A.V. Zubov, E.N. Borzunov, A.G. Mihin // Mater. dokl. nauchn. konf. «Teoriya i praktika bor'by s parazitarnymi boleznyami», VIGIS - Moskva, 2009 - S. 22-26.
3. Arhipov, I.A. Gel'mintozy sobak i koshek v krupnyh megapolisah Rossii / I.A. Arhipov, D.A. Avdanina, C.B. Lihotina // Veterinariya. - 2006. - № 3. - S. 33-38.
4. Arhipov, I.A. Zooparazitozy, peredavaemye cheloveku ot sobak i koshek / I.A. Arhipov, E.N. Borzunov, V.I. Shaykin // Materialy IX Mezhdunar. Mosk. vet. kongressa po boleznyam melkih domashnih zhivotnyh, 2001. - S. 230-231.
5. Arhipov, I.A. Rasprostranenie gel'mintozov sobak i koshek v Rossii i primenenie Prazitela dlya bor'by s nimi / I.A. Arhipov, O.A. Zeynalov, L.M. Kokorina, D.A. Avdanina, S.V. Lihotina // Rossiyskiy veterinarnyy zhurnal. - 2005. - № 2. - S. 26-30.
6. Bespalova, N.S. Epizootologiya ryada gel'mintozov sobak v usloviyah goroda N.S. Bespalova // Veterinariya. - 2003. - № 1. - S. 31-32.
7. Borzunov, A.G. Mihin // Mater. dokl. nauchn. konf. «Teoriya i praktika bor'by s parazitarnymi boleznyami», VIGIS - Moskva, 2009. - S. 22-26.
8. Vasilevich, F.I. Parazitarnye bolezni plotoyadnyh zhivotnyh / F.I. Vasilevich, N.V. Esaulova, R.M. Akbaev. - M., 2010. - 150 s.
9. Gerke, B.C. Opasnost' inficirovaniya cheloveka Toxocara canis pri kontakte s zarazhennymi sobakami // B.C. Gerke, A.N. Gerke, D.G. Tischenko // Veterinar. - 2005. - № 1. - S. 15.
10. Esaulova, N.V. Gel'mintozy sobak i koshek, opasnye dlya cheloveka, i ih diagnostika / N.V. Esaulova // Veterinariya. - 2000. - № 6. - S. 22-29.
11. Esaulova, N.V. Gel'mintofauna domashnih i dikih plotoyadnyh v usloviyah Central'noy zony Nechernozem'ya i usovershenstvovanie mer bor'by s osnovnymi gel'mintozami: spec. 03.00.19 «Parazitologiya»: avtoref. … kand. vet. nauk / N.V. Esaulova. - M., 2002. - 17 s.
12. Zaichenko, I.V. Gel'mintozy plotoyadnyh gorodskoy populyacii: rasprostranenie, diagnostika, lechenie: spec. 03.02.11 «Parazitologiya»: diss. ... kand. vet. nauk / I.V. Zaichenko. - Stavropol', 2012. - 124 s.
13. Kryuchkova, E.N. Ekologiya gel'mintov u domashnih i dikih plotoyadnyh zhivotnyh v evropeyskoy chasti Rossiyskoy Federacii: spec. 03.02.11 «Parazitologiya», 06.02.01 «Diagnostika bolezney i terapiya zhivotnyh, patologiya, onkologiya i morfologiya zhivotnyh»: diss. ... dokt. vet. nauk / E.N. Kryuchkova. - Ivanovo, 2012. - 311 s.
14. Orobec, V.A. Toksikologicheskaya ocenka antigel'mintnogo preparata dlya sobak i koshek Supramil® tabletki / V.A. Orobec, S.V. Mukaseev. O.A. Zeynalov // Veterinariya. - 2022. - №2. - S. 31-39.
15. Ostraya peroral'naya toksichnost' substancii R-prazikvantela (organizaciya-razrabotchik OOO «NVP «Astrafarm», Rossiya) na laboratornyh zhivotnyh. Otchet o NIR. 2015. OOO «MNIC «OZOS», 12 s.
16. Patent RU 2613490 C2. Kompoziciya na osnove R(-)-prazikvantela dlya lecheniya i profilaktiki gel'mintozov u teplokrovnyh. Vladelec patenta: Obschestvo s ogranichennoy otvetstvennost'yu "Nauchno-proizvodstvennaya kompaniya «SKiFF". Avtor: Zolotareva Vera Anatol'evna. Nachalo deystviya: 2015.01.27. Publikaciya: 2017.03.16. Podacha: 2015.01.27.
17. Patent RU 2722272 C1. Sredstvo dlya lecheniya i profilaktiki nematodozov i cestodozov u melkih domashnih zhivotnyh Vladelec patenta: Obschestvo s ogranichennoy otvetstvennost'yu "Nauchno-proizvodstvennaya kompaniya «SKiFF». Avtory: Kokorina Lyubov' Mihaylovna, Zeynalov Orhan Ahmed ogly. Nachalo deystviya: 2019.04.30. Publikaciya: 2020.05.28. Podacha: 2019.04.30.
18. Petrov, Yu.F. Kontaminaciya ob'ektov vneshney sredy yaycami i lichinkami Ancylostoma caninum i Uncinaria stenocephala v evropeyskoy chasti Rossii / Yu.F. Petrov, E. N. Kryuchkova, H. H. Shahbiev i dr. // Rossiyskiy parazitologicheskiy zhurnal. - 2012. - № 1. - S. 42-44.
19. Peshkov, R.A. Epizootologicheskaya situaciya po toksokarozu u plotoyadnyh i gel'mintologicheskaya ocenka vneshney sredy v megapolise Moskva: spec. 03.02.11 «Parazitologiya»: diss. ... kand. vet. nauk / R.A. Peshkov. - M., 2010. - 138 s.
20. Prazitel Osobyy. Unikal'noe reshenie dlya profilaktiki i lecheniya gel'mintozov u koshek i sobak starshe 6 let. - VetPharma - 2017. - №3 (37). - S. 20-27.
21. Orobec, V.A. Effektivnost' novogo antigel'mintnogo preparata Prazitel® Osobyy pri lechenii kishechnyh gel'mintozov sobak starshe 6 let / V.A. Orobec, O.I. Sevost'yanova, I.V. Zaichenko, S.V. Mukaseev // Rossiyskiy veterinarnyy zhurnal. - 2018. - № 2. - S. 45-48.
22. Orobec, V.A. Ocenka terapevticheskoy effektivnosti suspenzii Prazitel® Osobyy pri kishechnyh gel'mintozah schenkov i kotyat / V.A. Orobec, O.I. Sevost'yanova, I.V. Zaichenko, S.V. Mukaseev // Rossiyskiy veterinarnyy zhurnal. - 2019. - №7 - S. 25-32.
23. Sogrina, A.V. Parazitarnye zoonozy sluzhebnyh sobak goroda Permi / A.V. Sogrina, T.N. Sivkova // Izvestiya Samarskogo nauchnogo centra Rossiyskoy akademii nauk. - 2014. - T. 16. - № 5-1. - S. 518-520.
24. Fadeeva, A.N. Parazitarnye bolezni domashnih plotoyadnyh v usloviyah Nizhnego Novgoroda / A.N. Fadeeva, N.G. Gorchakova // Veterinariya. - 2016. - №. 6. - S. 33-35.
25. Farhutdinova, A.F. Gel'mintofauna, epizootologicheskaya situaciya po toksokarozu sobak i mery bor'by s nim v Srednem Povolzh'e: spec. 03.02.11 «Parazitologiya»: avtoref. dis. … kand. vet. nauk / A.F. Farhutdinova. - Ivanovo, 2014. - 22 s.
26. Hrapay, V.A. Parazitofauna domashnih i dikih plotoyadnyh zhivotnyh Yuga Rossii i mery bor'by s osnovnymi parazitozami: spec. 03.02.11 «Parazitologiya»: diss. ... kand. vet. nauk / V.A. Hrapay. - M., 2013. - 144 s.
27. Cherepanov, A.A. Atlas. Differencial'naya diagnostika gel'mintozov po morfologicheskoy strukture yaic i lichinok vozbuditeley / A.A. Cherepanov, A.S. Moskvin, G.A. Kotel'nikov, V.M. Hrenov. - M.: Kolos, 2001. Andrews P., Thomas H., Pohlke R., Seubert J. 76 s.
28. Chislo domashnih zhivotnyh v RF vyroslo na 14 % za tri goda: [Elektronnyy resurs]. - URL: https://www.interfax.ru/russia/631927 (data obrascheniya 26.12.2019).
29. Andrews, P. Praziquantel / P. Andrews, H. Thomas, R. Pohlke, J. Seubert // Med. Res. Rev. - 1983. No. - 3, pp. 147-200.
30. Cioli, D. Schistosomiasis control: Praziquantel forever? / D. Cioli, L. Pica-Mattoccia, A. Basso, A Guidi. // Mol Biochem Parasitol. - 2014. - No. 195(1). - pp. 23-29.
31. Liu, Y.H. Levo-praziquantel versus praziquantel in experimental and clinical treatment of schistosomiasis japonica / Y.H. Liu, M.X. Qian, X.G Wang. et al. // Chin. Med. J. (Engl). 1993. - No. 106. - rr. 593-596.
32. Liu, Y.H. Comparative efficacy of praziquantel and its optic isomers in experimental therapy of schistosomiasis japonica in rabbits / Y.H. Liu, M.X. Qian, X.G Wang. et al. // Chin. Med. J. (Engl). - 1986. - No. 99. - rr. 935-940.
33. Meister, I. Activity of praziquantel enantiomers and main metabolites against Schistosoma mansoni / I. Meister, K. Ingram-Sieber, N. Cowan, M. Todd, M.N. Robertson, C. Meli, M. Patra, G. Gasser, J. Keiser // Antimicrob Agents Chemother. - 2014 Sep. - Vol. 30. - No. 58(9). - pp. 5466-5472.
34. Meyer, T. Taste, a new incentive to switch to (R)-Praziquantel in schistosomiasis treatment / T. Meyer, H. Sekljic, S. Fuchs, H. Bothe, D. Schollmeyer, C. Miculka // PLoS Negl. Trop. Dis. - 2009. - No. 3. - r. 357.
35. Olliaro, P. The little we know about the pharmacokinetics and pharmacodynamics of praziquantel (racemate and R-enantiomer) / P. Olliaro, P. Delgado-Romero, J. Keiser // J. Antimicrob. Chemother. - 2014. - No. 69(4). - rr. 863-870.
36. Shuhua, X. Tegumental changes in adult Schistosoma mansoni harboured in mice treated with praziquantel enantiomers / X. Shuhua, S. Binggui, J. Chollet, M. Tanner // Acta Trop. - 2000 Sep. - Vol. 18. No. 76(2). - pp. 107-117.
37. Tanaka, M. A comparison of the antischistosomal effect of levo- and dextro-praziquantel on Schistosoma japonicum and S. mansoni in mice / M. Tanaka, H. Ohmae, H. Utsunomiya, T. Nara, Y. Irie, K. Yasuraoka // Am. J. Trop. Med. Hyg. - 1989. - No. 41. - rr. 198-203.
38. Wu, M.H. Comparison of the therapeutic efficacy and side effects of a single dose of levo-praziquantel with mixed isomer praziquantel in 278 cases of schistosomiasis japonica / M.H. Wu, C.C. Wei, Z.Y Xu. et al. // Am. J. Trop. Med. Hyg. - 1991. - No. 45. - rr. 345-349.
39. Xiao, S. Scanning electron microscope observation on tegumental alteration of Schistosoma japonicum induced by levo- and dextro-praziquantel / S. Xiao, B. Shen // Institute of Parasitic Diseases, Chinese Academy of Preventive Medicine, Shanghai, - 1995. - No. 13(1). - pp. 46-50.
