EXTRA-INTESTINAL MANIFESTATIONS OF CROHN DISEASE AND CHRONIC ULCERATIVE COLITIS IN THE ORAL CAVITY

Rita Yunusova; Irina Usmanova; Amina Ishmukhametova; Larisa Gerasimova; Yigal Granot; Elmina Kgarmanova; Rauza Khusnarizanova; Alina Sarvalieva

doi:doi:10.18481/2077-7566-21-17-4-32-38

UDC 61631

EXTRA-INTESTINAL MANIFESTATIONS OF CROHN DISEASE AND CHRONIC ULCERATIVE COLITIS IN THE ORAL CAVITY

Published в Actual problems in dentistry · Volume 17, Issue 4, 2021 · Pages 32–38 · Rubrics: LITERATURE REVIEW

DOI 10.18481/2077-7566-21-17-4-32-38

Received: 03.12.2021 Accepted: 10.12.2021 Published: 28.12.2021 Language of publication: ENG

Authors

Rita Yunusova ¹ · Irina Usmanova ² · Amina Ishmukhametova ³ · Larisa Gerasimova ⁴ · Yigal Granot ⁵ · Elmina Kgarmanova ⁶ · Rauza Khusnarizanova ⁷ · Alina Sarvalieva ⁸

1 Bashkir State Medical Universitey (Department of Therapeutic Dentistry with a course IDPO)
Ufa, Ufa, Russian Federation

2 Bashkirian State Medical University (Department of Therapeutic Dentistry with the course of ICPE, Professor of the Department)
Ufa, Ufa, Russian Federation

3 Bashkirian State Medical University (Department of Internal diseases, Docent of Department)
Ufa, Kazan, Russian Federation

4 Bashkirskiy gosudarstvennyy medicinskiy universitet (professor, zaveduyuschaya kafedroy terapevticheskoy stomatologii s kursom IPO)
Ufa, Ufa, Russian Federation

5 Institute of Maxilofacial Surgery, Oral Medicine and Dentistry, Bar Ilan University School of Medicine, Galilee Medical Center (Department of Hospital Oral Medicine, Head of the Department)
Nagariya, Israel

6 City Clinical Hospital No. 21 (Gastroenterology Department, Head of department)
Ufa, Ufa, Russian Federation

7 Bashkir State Medical Universitey (Department of Microbiology and Virology, Docent)
Ufa, Ufa, Russian Federation

8 Bashkirian State Medical University
Ufa, Ufa, Russian Federation

ABSTRACT

Subject. The review allows us to consider the issues of etiopathogenesis, the prevalence of Crohn disease and ulcerative colitis, as well as their manifestations on the oral mucosa. The aim is to conduct a systematic analysis of modern indigenous and foreign literary sources to determine some features of etiopathogenesis, prevalence and manifestations in the oral cavity of Crohn disease and chronic non-specific ulcerative colitis. Methodology. The search for research works on the etiology and pathogenesis of Crohn disease, ulcerative colitis was carried out using the following databases: PubMed, Web of Science, elibrary.ru , Scopus in the period from 2010 to 2021, as well as the review includes some significant publications concerning the manifestations in the oral cavity of CD and NCUC for the period from 2014 to 2021. The following keywords were used: chronic ulcerative colitis, Crohn disease, caries, periodontal disease, oral mucosa, aphthae, dysbiosis. Results. Among the main dental diseases, pathology of hard tissues, inflammatory diseases of periodontal tissues, pathology of the oral mucosa against the background of pronounced dysbiosis most often prevails. During a comprehensive examination of these patients, it is very important to analyze not only the features of the manifestations of Crohn disease and ulcerative colitis, but also to evaluate their manifestations on the hard tissues of the teeth, the oral mucosa and periodontal tissues. Conclusions. Thus, the analysis of the literature data obtained is of particular relevance for identifying some features of the state of dental status in CD and NCUC in the Republic of Bashkortostan and the basis for the development of algorithms for diagnostic features of the management of this category of persons.

KEYWORDS

chronic nonspecific ulcerative colitis Crohn disease caries periodontal disease oral mucosa aphthae candidiasis

Information References

Authors:

1. Bashkir State Medical Universitey (Department of Therapeutic Dentistry with a course IDPO)

Ufa, Ufa, Russian Federation

2. Bashkirian State Medical University (Department of Therapeutic Dentistry with the course of ICPE, Professor of the Department)

Ufa, Ufa, Russian Federation

3. Bashkirian State Medical University (Department of Internal diseases, Docent of Department)

Ufa, Kazan, Russian Federation

4. Bashkirskiy gosudarstvennyy medicinskiy universitet (professor, zaveduyuschaya kafedroy terapevticheskoy stomatologii s kursom IPO)

Ufa, Ufa, Russian Federation

5. Institute of Maxilofacial Surgery, Oral Medicine and Dentistry, Bar Ilan University School of Medicine, Galilee Medical Center (Department of Hospital Oral Medicine, Head of the Department)

Nagariya, Israel

6. City Clinical Hospital No. 21 (Gastroenterology Department, Head of department)

Ufa, Ufa, Russian Federation

7. Bashkir State Medical Universitey (Department of Microbiology and Virology, Docent)

Ufa, Ufa, Russian Federation

8. Bashkirian State Medical University

Ufa, Ufa, Russian Federation

Type:

Article

Pages:

from 32 to 38

Status:

Published

Subject area:

UDC 61631

Language:

English

Keywords:

chronic nonspecific ulcerative colitis, Crohn disease, caries, periodontal disease, oral mucosa, aphthae, candidiasis

References

1. Avalueva E.B., Bakulin I.G., Sitkin S.I., Vorob'ev S.L., Belyakov I.A., Trushnikova N.A., Karpeeva Yu.S. Bolezn' Krona s izolirovannym porazheniem zheludka kak primer redkogo fenotipa zabolevaniya: klinicheskoe nablyudenie. Al'manah klinicheskoy mediciny. 2019;47(6):592-602. [E.B. Avalueva, I.G. Bakulin, S.I. Sitkin, S.L. Vorobyev, I.. Belyakov, N.A. Trushnikova, Yu.S. Karpeeva. Crohn’s disease with isolated gastric involvement as an example of a rare disease phenotype: a clinical case. Almanac of Clinical Medicine. 2019;47(6):592-602. (In Russ.)]. https://doi.org/10.18786/2072-0505-2019-47-074

2. Robakidze N.S., Baranovskiy A.Yu. Analiz techeniya recidiviruyuschego aftoznogo stomatita u bol'nyh s vospalitel'nymi zabolevaniyami kishechnika. Institut stomatologii. 2016;1(70):58-59. [N.S. Robakidze, A.Yu. Baranovsky. The analysis of recurrent aphthous stomatitis of the patients with inflammatory bowel disease. The Dental Institute. 2016;1(70):58-59. (In Russ.)]. https://elibrary.ru/item.asp?id=25844124

3. Andronova N.A., Mamaeva M.I., Mitronin A.V. Stomatologicheskiy status pacientov, stradayuschih yazvennym kolitom, na fone biologicheskoy terapii selektivnym immunodepressantom (monoklonal'nye antitela k FNO-α). Rossiyskaya stomatologiya. 2014;7(2):39-42. [N.A. Andronova, M.I. Mamaeva, A.V. Mitronin. The dental status of the patients presenting with ulcerative colitis during biological therapy with a selective immunodepressant (monoclonal anti-TNF-α antibodies). Russian Stomatology. 2014;7(2):39-42. (In Russ.)]. https://elibrary.ru/item.asp?id=22364426

4. Schukina O.B., Robakidze N.S., Nasyhova Yu.A. Associaciya polimorfizma gena nod 2/card 15 s aftoznym stomatitom pri bolezni Krona. Eksperimental'naya i klinicheskaya gastroenterologiya. 2017;10(146):46-49. [O.B. Shchukina, N.S. Robakidze, J.A. Nasykhova. Association of polymorphism of the nod 2/ card 15 gene with aphthous stomatitis in crohn’s disease. Experimental and clinical gastroenterology journal. 2017;10(146):46-49. (In Russ.)]. https://elibrary.ru/item.asp?id=32405812

5. Ahrieva H.M., Tertychnyy A.S., Maev I.V., Zayrat'yanc O.V. Klassifikaciya i morfologicheskaya diagnostika yazvennogo kolita i bolezni Krona. Klinicheskaya i eksperimental'naya morfologiya. 2017;3:4-15. [Kh.M. Akhrieva, A.S. Tertychniy, I.V. Maev, O.V. Zayratyants. Classification and morphological diagnosis of ulcerative colitis and crohn’s disease. Clinical And Experimental Morphology. 2017;3:4-15. (In Russ.)]. https://elibrary.ru/item.asp?id=29946271

6. Bakulin I.G., Skalinskaya M.I., Skazyvaeva E.V. «Trudnye» voprosy pri vedenii pacientov s vospalitel'nymi zabolevaniyami kishechnika. Mediko-social'naya ekspertiza i reabilitaciya. 2018;21(1-2):94-100. [I.G. Bakulin, M.I. Skalinskaya, E.V. Skazyvaeva. “Difficult” issues of the management of inflammatory bowel diseases patients. Medical and Social Expert Evaluation and Rehabilitation, Russian Journal. 2018;21(1-2):94-100. (In Russ.)]. http://doi.org/10.18821/1560-9537-2018-21-1-94-100

7. Belousova E.A., Abdulganieva D.I., Alekseeva O.P. i dr. Social'no-demograficheskaya harakteristika, osobennosti techeniya i varianty lecheniya vospalitel'nyh zabolevaniy kishechnika v Rossii. Rezul'taty dvuh mnogocentrovyh issledovaniy. Al'manah klinicheskoy mediciny. 2018;46(5):445-463. [E.A. Belousova, D.I. Abdulganieva, O.P. Alexeeva et al. Social and demographic characteristics, features of disease course and treatment options of inflammatory bowel disease in Russia: results of two multicenter studies. Almanac of Clinical Medicine. 2018;46(5):445-463. (In Russ.)]. https://doi.org/10.18786/2072-0505-2018-46-5-445-463

8. Bodryagina E.S., Abdulganieva D.I., Schdincova A.H. Kliniko-epidemiologicheskie pokazateli vospalitel'nyhzabolevaniy kishechnika po Respublike Tatarstan. Lechaschiy vrach. 2013;7:21-26. [E.S. Bodryagina, D.I. Abdulganieva, A.H. Odintsovo. The Clinico-epidemiological indices of intestine inflammatory diseases in the republic of Tatarstan. Therapist. 2013;7:21-26. (In Russ.)]. https://elibrary.ru/item.asp?id=22474147

9. Grinevich V.B., Kravchuk Yu.A., Ped' V.I. i dr. Vedenie pacientov s zabolevaniyami organov pischevareniya v period pandemii COVID-19. Klinicheskie rekomendacii Nauchnogo obschestva gastroenterologov Rossii. Eksperimental'naya i klinicheskaya gastroenterologiya. 2020;7(179):4-51. [V.B. Grinevich, Yu.A. Kravchuk, V.I. Ped. et al. Management of patients with digestive diseases during the covid-19 pandemic: clinical practice guidelines by the gastroenterological scientific society of Russia. Experimental and clinical gastroenterology journal. 2020;7(179):4-51. (In Russ.)]. http://dx.doi.org/10.31146/1682-8658-ecg-179-7-4-51.

10. Klyaritskaya I.L., Stilidi E.I., Maksimova E.V., Shahbazidi G. Vnekishechnye proyavleniya vospalitel'nyh zabolevaniy kishechnika. Krymskiy Terapevticheskiy Zhurnal. 2017;1(32):47-51. [I.L. Kliaritskaia, E.I. Stilidi, E.V. Maksimova, G. Shakhbazidi. Extraintestinal manifestations of inflammatory bowel disease. Crimean journal of internal diseases. 2017;1(32):47-51. (In Russ.)]. https://elibrary.ru/item.asp?id=28367558

11. Gubonina I.V., Grinevich V.B., Tkachenko E.I. i dr. Kliniko-epidemiologicheskaya harakteristika i ishody vospalitel'nyh zabolevaniy kishechnika v kogorte bol'nyh po dannym vos'miletnego nablyudeniya. Eksperimental'naya i klinicheskaya gastroenterologiya. 2019;172(12):24-33. [I.V. Gubonina, V.B. Grinevich, E.I. Tkachenko et al. Clinical and epidemiological characteristics and outcomes of infl amatory bowel diseases according to 8-year follow-up in a cohort of patients in the North-West region. Experimental and Clinical Gastroenterology. 2019;172(12):24-33. (In Russ.)]. https://doi.org/10.31146/1682-8658-ecg-172-12-24-33

12. Dolgushina A.I., Husainova G.M., Vasilenko A.G., Kononec V.A. Rasprostranennost' vospalitel'nyh zabolevaniy kishechnika v Chelyabinskoy oblasti. Al'manah klinicheskoy mediciny. 2019;47(6):511-517. [A.I. Dolgushina, G.M. Khusainova, A.G. Vasilenko, V.A. Kononets. Prevalence of inflammatory bowel disease in the Chelyabinsk Region. Almanac of Clinical Medicine. 2019;47(6):511-517. (In Russ.)]. https://doi.org/10.18786/2072-0505-2019-47-066

13. Robakidze N.S. Kliniko-morfologicheskie i immunogistohimicheskie osobennosti patologii slizistoy obolochki polosti rta pri vospalitel'nyh zabolevaniyah kishechnika : avtoref. dis. ... doktora medicinskih nauk. [Sev.-Zap. gos. med. un-t.] Sankt-Peterburg, 2016:22. [N.S. Robakidze. Clinical, morphological and immunohistochemical features of pathology of the oral mucosa in inflammatory bowel diseases : abstract of the dissertation ... Doctors of Medical sciences. Sev.-Zap. gos. med. un-T. Saint Petersburg, 2016:22. (In Russ.)]. ]https://elibrary.ru/item.asp?id=30445655

14. Robakidze N.S., Cimbalistov A.V., Baranovskiy A.Yu. Kliniko-morfologicheskie i immunogistohimicheskie osobennosti slizistoy obolochki rta pri bolezni Krona i yazvennom kolite. Golova i sheya. 2017;3:40-45. [N.S. Robakidze, A.V. Tzimbalistov, A.Yu. Baranovsky. Clinical, morphological and immunohistochemical specifics of oral cavity mucosa in patients with crohn’s disease and ulcerous colitis. Head and neck. 2017;3:40-45. (In Russ.)]. https://elibrary.ru/item.asp?id=335058551

15. Klinicheskie rekomendacii po diagnostike i lecheniyu bolezni krona u vzroslyh (proekt). Koloproktologiya. 2020;19(2):8-38. [Crohn's disease. Clinical recommendations (preliminary version). Koloproktologia. 2020;19(2):8-38. (In Russ.)]. https://doi.org/10.33878/2073-7556-2020-19-2-8-38

16. Mitronin A.V., Andronova N.A. Klinicheskoe issledovanie chastoty vstrechaemosti vospalitel'nyh zabolevaniy parodonta u pacientov, stradayuschih yazvennym kolitom. Dental Forum. 2017;4:60. [A.V. Mitronin, N.A. Andronova. Clinical investigation of prevalence of inflammatory periodontal diseases in patients with ulcerative colitis. Dental Forum. 2017;4:60. (In Russ.)]. https://elibrary.ru/item.asp?id=30504306

17. Kolomiec S.V., Udal'cova K.A., Shinkevich V.I. Debyut bolezni Krona v polosti rta. Klinicheskiy sluchay. Stomatologiya. 2017;96(5):28-30. [S.V. Kolomiets, K.A. Udaltsova, V.I. Shinkevich. Crohn's disease debut in the oral cavity. Case report Dentistry. 2017;96(5):28-30. (In Russ.)]. https://doi.org/10.17116/stomat201796528-30

18. Tytyuk S.Yu., Pihur O.L., Tishkov D.S., Iordanishvili A.K. Morfofunkcional'nye osobennosti slizistoy obolochki polosti rta lic, stradayuschih hronicheskimi vospalitel'nymi zabolevaniyami kishechnika. Kurskiy nauchno-prakticheskiy vestnik «Chelovek i ego zdorov'e». 2016;3:49-55. [S.Yu. Tityuk, O.L. Pikhur, D.S. Tishkov, A.K. Iordanishvili. Morphological and functional features of oral mucosa in persons with chronic inflammatory bowel diseases. Kursk scientific and practical bulletin "Man and his health". 2016;3:49-55. (In Russ.)]. https://doi.org/10.21626/vestnik/2016-3/08

19. Nazirbekova M.M., Abasova A.S. Struktura zabolevaemosti vospalitel'nymi zabolevaniyami kishechnika v Dagestane za poslednie 5 let. Kardiovaskulyarnaya terapiya i profilaktika. 2021;20(1S):61. [M.M. Nazirbekova, A.S. Abasova. The structure of the incidence of inflammatory bowel diseases in Dagestan over the past 5 years. Cardiovascular therapy and prevention. 2021;20(1S):61. (In Russ.)]. https://doi.org/10.15829/1728-8800-2021-1S

20. Tytyuk S.Yu., Iordanishvili A.K., Romanenko I.G. Osobennosti morfologicheskogo stroeniya i himicheskogo sostava tverdyh tkaney zubov pri bolezni Krona i hronicheskom nespecificheskom yazvennom kolite. Vestnik medicinskogo instituta «REAVIZ»: Reabilitaciya, Vrach I Zdorov'e. 2019;1(37):88-92. [S.Yu. Tytyuk, A.K. Iordanishvili, I.G. Romanenko. Morphological structure and chemical composition of hard dental tissues in patients with crohn's disease and chronic ulcerative colitis. Bulletin of the medical Institute "REAVIZ": Rehabilitation, Doctor And Health. 2019;1(37):88-92. (In Russ.)]. https://elibrary.ru/item.asp?id=37634606

21. Tytyuk S.Yu., Pihur O.L., Shulutko B.I., Iordanishvili A.K., Karev F.A., Vasil'ev A.V. Porazheniya organov i tkaney polosti rta pri hronicheskih vospalitel'nyh zabolevaniyah kishechnika u vzroslogo cheloveka. Kurskiy nauchno-prakticheskiy vestnik Chelovek i ego zdorov'e. 2015;3:49-55. [S.Yu. Tytyuk, O.L. Pikhur, B.I. Shulutko, A.K. Iordanishvili, F.A. Karev, A.V. Vasiliev. Lesions of organs and tissues of oral cavity in chronic inflammatory bowel diseases in adults. Kursk scientific and practical bulletin man and his health. 2015;3:49-55. (In Russ.)]. https://elibrary.ru/item.asp?id=24394965

22. Robakidze N.S. Profilaktika recidiviruyuschego stomatita pri bolezni krona. Profilaktika v stomatologii : materialy mezhdunarodnoy nauchno-prakticheskoy konferencii. Severo-Zapadnyy gosudarstvennyy medicinskiy universitet imeni I.I. Mechnikova ; Nauchnoe medicinskoe obschestvo stomatologov Sankt-Peterburga. 2019:70-73. [N.S. Robakidze. Prevention of recurrent stomatitis in Crohn's disease. Prevention in dentistry. Materials of the international scientific and practical conference. North-Western State Medical University named after I.I. Mechnikov ; Scientific Medical Society of Dentists of St. Petersburg. 2019:70-73. (In Russ.)]. https://elibrary.ru/item.asp?id=37273519

23. Robakidze N.S., Baranovskiy A.Yu., Schukina O.B., Kiseleva E.B. Differencial'no-diagnosticheskie kriterii bolezni Krona i yazvennogo kolita po sostoyaniyu slizistoy obolochki rta. Institut stomatologii. 2014;3(64):58-59. [N.S. Robakidze, A.Yu. Baranovsky, O.B. Shchukina, E.B. Kiseleva. Diff erential-diagnostic criteria crohn’s disease and ulcerative colitis based on the status of the oral mucosa. The Dental Institute. 2014;3(64):58-59. (In Russ.)]. https://elibrary.ru/item.asp?id=22988384

24. Robakidze N.S. Optimizaciya differencial'noy diagnostiki vospalitel'nyh zabolevaniy kishechnika na osnovanii kompleksnoy ocenki stomatologicheskogo statusa. Sovremennye tehnologii v medicine. 2015;7(1):81-88. [N.S. Robakidze. Optimization of Differential Diagnosis of Inflammatory Bowel Diseases Based on an Integrated Assessment of Oral Mucosa Status. Modern Technologies In Medicine. 2015;7(1):81-88. (In Russ.)]. https://dx.doi.org/10.17691/stm2015.7.1.11

25. Robakidze N.S., Schukina O.B. Patogeneticheskie aspekty porazheniya polosti rta pri vospalitel'nyh zabolevaniyah kishechnika. Rossiyskiy zhurnal gastroenterologii, gepatologii, koloproktologii. 2019;29(4):15-21. [N.S. Robakidze, O.B. Shchukina. Pathogenetic Aspects of Oral Cavity Lesions in Inflammatory Gastrointestinal Tract Diseases. Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2019;29(4):15-21. (In Russ.)]. https://doi.org/10.22416/1382-4376-2019-29-4-15-21

26. Svatkova O.A., Sheptulin A.A. Prichiny oshibok v diagnostike hronicheskih vospalitel'nyh zabolevaniy kishechnika v obschey vrachebnoy praktike. Rossiyskiy zhurnal gastroenterologii, gepatologii, koloproktologii. 2020;30(5):26-29. [O.A. Svatkova, A.A. Sheptulin. Sources of Bias in Common Diagnosis of Chronic Inflammatory Bowel Diseases. Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2020;30(5):26-29. (In Russ.)]. https://doi.org/10.22416/1382-4376-2020-30-5-26-29

27. Mamaeva M.I. Sovremennye metody ustraneniya galitoza na fone bolezni Krona : diss. ... kand. med. nauk [FGBOU VO Moskovskiy gosudarstvennyy mediko-stomatologicheskiy universitet imeni A.I. Evdokimova Ministerstva zdravoohraneniya Rossiyskoy Federacii]. 2017:172. [M.I. Mamayeva. Modern methods of halitosis elimination against the background of Crohn's disease : diss. ... Cand. Med. Sciences. Moscow State Medical and Dental University named after A.I. Evdokimov of the Ministry of Health of the Russian Federation. 2017:172. (In Russ.)]. https://www.dissercat.com/content/sovremennye-metody-ustraneniya-galitoza-na-fone-bolezni-krona

28. Robakidze N.S., Pihur O.L. Sostoyanie tverdyh tkaney zubov pacientov s vospalitel'nymi zabolevaniyami kishechnika v raznyh vozrastnyh gruppah. Nauchnye vedomosti Belgorodskogo gosudarstvennogo universiteta. Seriya: Medicina. Farmaciya. 2015;16(213):266-271. [N.S. Robakidze, O.L. Pikhur. Condition of hard tooth tissues of patients with inflammatory intestinal diseases in different age groups. Scientific bulletin of Belgorod state university. Series: medicine. Pharmacy. 2015;16(213):266-271. (In Russ.)]. https://elibrary.ru/item.asp?id=24910369

29. Andronova N.A. Sravnitel'naya ocenka rasprostranennosti i intensivnosti kariesa zubov u pacientov, stradayuschih yazvennym kolitom. Dental Forum. 2017;4:12. [N.A. Andronova. The comparative assessment of dental caries prevalence in patients with ulcerative colitis. Dental Forum. 2017;4:12. (In Russ.)]. https://elibrary.ru/item.asp?id=30504265

30. Shipicyna M.S., Tytyuk S.Yu., Iordanishvili A.K. Stomatologicheskaya zabolevaemost' pri bolezni krona i hronicheskom nespecificheskom yazvennom kolite. Medicina: teoriya i praktika. 2018;3(1):121. [M.S. Shipitsyna, S.Yu. Tytyuk, A.K. Iordanishvili. Dental morbidity in crohn's disease and chronic ulcerative colitis. Medicine: theory and practice. 2018;3(1):121. (In Russ.)]. https://elibrary.ru/item.asp?id=35173994

31. Truhan L.Yu., Truhan D.I. Ctomatologicheskie problemy gastroenterologicheskih pacientov i vozmozhnye puti ih resheniya. Medicinskiy Sovet. 2016;(19):134-137. [L.Yu. Trukhan, D.I. Trukhan. Stomatoligical problems of gastroenterological patients and their possible solutions. Meditsinskiy sovet Medical Council. 2016;(19):134-137. (In Russ.)]. https://doi.org/10.21518/2079-701X-2016-19-134-137

32. Halif I.L., Shapina M.V., Golovenko A.O. i dr. Techenie hronicheskih vospalitel'nyh zabolevaniy kishechnika i metody ih lecheniya, primenyaemye v Rossiyskoy Federacii (Rezul'taty mnogocentrovogo populyacionnogo odnomomentnogo nablyudatel'nogo issledovaniya). Rossiyskiy zhurnal gastroenterologii, gepatologii, koloproktologii. 2018;28(3):54-62. [I.L. Khalif, M.V. Shapina, A.O. Golovenko et al. Chronic inflammatory bowel diseases: the course and treatment methods in Russian Federation (Results of multicenter population-based one-stage observational study). Rus J Gastroenterol Hepatol Coloproctol. 2018;28(3):54-62. (In Russ.)]. https://doi.org/10.22416/1382-4376-2018-28-3-54-62

33. Tytyuk S.Yu., Iordanishvili A.K. Harakteristika tverdyh tkaney zubov pri hronicheskih vospalitel'nyh zabolevaniyah kishechnika u vzroslyh. Krymskiy terapevticheskiy zhurnal. 2019;1:67-71. [S.Yu. Tytyk, A.K. Iordanishvili. Characteristics of hard dental tissues in chronic inflammatory bowel diseases in adults. Crimean Journal Of Internal Diseases. 2019;1:67-71. (In Russ.)]. https://elibrary.ru/item.asp?id=37254905

34. Cimmerman Ya.C., Cimmerman I.Ya., Tret'yakova Yu.I. Yazvennyy kolit i bolezn' Krona: sovremennye predstavleniya chast' 1. Definiciya, terminologiya, rasprostranennost', etiologiya i patogenez, klinika, oslozhneniya, klassifikaciya. Klinicheskaya medicina. 2013;11:27-33. [Ya.S. Tsimmerman, I.Ya. Tsimmerman, Yu.I. Tretiakova. Ulcerative colitis and Crohn’s disease. Modern views. Part 2. Diagnostics and differential therapy. Clinical medicine. 2013;11:27-33. (In Russ.)]. https://elibrary.ru/item.asp?id=21034393

35. Neganova O.A., Styazhkina S.N., Nikolaeva V.N., Muradova D.M. Yazvennyy kolit i bolezn' krona: retrospektivnaya ocenka zabolevaemosti za 2016-2018 gody. Zdorov'e i obrazovanie v XXI veke. 2019;21(6):40-43. [O.A. Neganova, S.N. Styazhkina, V.N. Nikolaeva, D.M. Muradova. Ulcerative colitis and crohn's disease: a retrospective assessment of morbidity for 2016-2018. The Journal of scientific articles “Health and Education Millennium” 2019;21(6):40-43. (In Russ.)]. http://dx.doi.org/10.26787/nydha-2226-7425-2019-21-6-40-43

36. Choon J.O., Govind K.M., Ida H., Peter R.G. et al. Asia Pacific Consensus Statements on Crohn's disease. Part 1: Definition, diagnosis, and epidemiology // Journal of Gastroenterology and Hepatology. - 2016;31:45-55. https://doi.org/10.1111

37. Bek S., Nielsen J.V., Bojesen A.B., Franke A., Bank S., Vogel U., Andersen V. Systematic review: genetic biomarkers associated with anti-TNF treatment response in inflammatory bowel diseases // Aliment Pharmacol Ther. - 2016;44(6):554-567. https://dx.doi.org/10.1111/apt.13736

38. Burisch J., Munkholm P. The epidemiology of inflammatory bowel disease // Scand J Gastroenterol. - 2015;50(8):942-951. https://dx.doi.org/10.3109/00365521.2015.1014407.

39. Cosnes J., Gower-Rousseau C., Seksik P., Cortot A. Epidemiology and natural history of infl ammatory bowel diseases // Gastroenterology. - 2011;140:1785-1794. https://dx.doi.org/10.1053/j.gastro.2011.01.055.

40. Dignass A., Assche G. Van, Lindsay J.O., Lémann M. et al. The second European evidence-based Consensus on the diagnosis and management of Crohn's disease: Current management // J Crohns Colitis. - 2010;4(1):28-62. https://dx.doi.org/10.1016/j.crohns.2009.12.002.

41. Esser D., Cornillie F., Diamond R.H., Spiegel .R.J. On the updated ECCO consensus guidelines for medical management of Crohn's disease // J Crohns Colitis. - 2011;5(2):165-166. https://dx.doi.org/10.1016/j.crohns.2010.02.002.

42. Vavricka S.R., Schoepfer A., Scharl M., Lakatos P. L, Navarini A., Rogler G. Extraintestinal Manifestations of Inflammatory Bowel Disease // Inflamm Bowel Dis. - 2015;21(8):1982-1992. https://dx.doi.org/10.1097/MIB.0000000000000392.

43. Fiocchi C. Inflammatory bowel disease pathogenesis: where are we? // J Gastroenterol Hepatol. - 2015;1;1:12-18. https://dx.doi.org/10.1111/jgh.12751.

44. Gafforov S.A., Fazilbekova G.A. A Scientific view of the problem of treatment and prevention of dental anomaly in children with diseases of bronchial asthma (review analysis of the literature) // Theoretical & Applied Science. - 2020;7(87):424-431. https://doi.org/10.15863/TAS.2020.07.87.81

45. Goodhand J., Dawson R., Hefferon M., Tshuma N., Swanson G., Wahed M., Croft N.M., Lindsay J.O. Inflammatory bowel disease in young people: the case for transitional clinics // Inflamm Bowel Dis. - 2010;16(6):947-952. https://doi.org/10.1002/ibd.21145.

46. Harbord M., Annese V., Vavricka S.R. et al. European Crohn’s and Colitis Organisation. The First European Evidence-based Consensus on Extraintestinal Manifestations in Inflammatory Bowel Disease // J Crohns Colitis. - 2016;10(3):239-254. https://doi.org/10.1093/ecco-jcc/jjv213

47. Berkowitz L., Schultz B.M., Salazar G.A., Pardo-Roa C. Impact of Cigarette Smoking on the Gastrointestinal Tract Inflammation: Opposing Effects in Crohn’s Disease and Ulcerative Colitis // Front. Immunol. - 2018. https://doi.org/doi.org/10.3389/fimmu.2018.00074

48. Ingle S.B., Adgaonkar B.D., Jamadar N.P., Siddiqui S., Hinge C.R.. Crohn's disease with gastroduodenal involvement: Diagnostic approach // World J Clin Cases. - 2015;3(6):479-483. https://doi.org/10.12998/wjcc.v3.i6.479.

49. Jajam M., Bozzolo P., Niklander S. Oral manifestations of gastrointestinal disorders // J Clin Exp Dent. - 2017;9(10):1242-1248. https://dx.doi.org/10.4317/jced.54008

50. Kaplan G.G. The global burden of IBD: from 2015 to 2025 // Nat Rev Gastroenterol Hepatol. - 2015;12(12):720-277. https://dx.doi.org/10.1038/nrgastro.2015.150

51. Li X., Song P., Li J., Tao Y., Li G., Li X. The Disease Burden and Clinical Characteristics of Inflammatory Bowel Disease in the Chinese Population: A Systematic Review and Meta-Analysis // Int J Environ Res Public Health. - 2017;14(3):E238. https://doi.org/10.3390/ijerph14030238

52. Lichtenstein G.R., Loftus E.V., Isaacs K.L., Regueiro M.D., Gerson L.B., Sands B.E. ACG Clinical Guideline: Management of Crohn's Disease in Adults // Am J Gastroenterol. - 2018;113(4):481-517. https://doi.org/10.1038/ajg.2018.27.

53. Loftus E.V. Jr. Update on the Incidence and Prevalence of Inflammatory Bowel Disease in the United States // Gastroenterol Hepatol (NY). - 2016;12(11):704-707. PMID: 28035199

54. Mokhtar N.M., Nawawi K.N.M., Verasingam J. et al. A four-decade analysis of the incidence trends, sociodemographic and clinical characteristics of inflammatory bowel disease patients at single tertiary centre, Kuala Lumpur, Malaysia // BMC Public Health. - 2019;19(4):550. https://doi.org/10.1186/s12889-019-6858-2

55. Muhvić-Urek M., Tomac-Stojmenović M., Mijandrušić-Sinčić B. Oral pathology in inflammatory bowel disease // World J Gastroenterol. - 2016;22(25):5655-5667. https://dx.doi.org/10.3748/wjg.v22.i25.5655

56. Longo S., Chieppa M., Cossa L.G., Spinelli C.C., Greco M., Maffia M., Giudetti A.M. New Insights into Inflammatory Bowel Diseases from Proteomic and Lipidomic // Studies Proteomes. - 2020;8(3):18. https://dx.doi.org/10.3390/proteomes8030018.

57. Ng S.C., Shi H.Y., Hamidi N. et al. Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies // Lancet. - 2018;390(10114):2769-2778. https://doi.org/10.1016/s0140-6736(17)32448-0

58. Nijakowski K., Surdacka A. Salivary Biomarkers for Diagnosis of Inflammatory Bowel Diseases:A Systematic Review // International Journal of Molecular Sciences. - 2020;21(20):7477. https://doi.org/10.3390/ijms21207477

59. Mortada I., Leone A., Gerges Geagea A., Mortada R., Matar C., Rizzo M., Hajj Hussein I., Massaad-Massade L., Jurjus A. Oral manifestations of inflammatory bowel disease // J. Biol Regul Homeost Agents. - 2017;31(3):817-821. PMID:28958141

60. Pereira M.S., Munerato M.C. Oral Manifestations of Inflammatory Bowel Diseases: Two Case Reports // Clin Med Res. - 2016;14(1):46-52. https://doi.org/10.3121/cmr.2015.1307. Epub 2016 Feb 10.

61. Agossa K., Dendooven A., Dubuquoy L., Gower-Rousseau C., Delcourt-Debruyne E., Capron M. Periodontal manifestations of inflammatory bowel disease: emerging epidemiologic and biologic evidence // J Periodont Res. - 2017;52:313-324. https://doi.org/10.1111/jre.12422

62. Pimentel A.M., Rocha R., Santana G.O. Crohn’s disease of esophagus, stomach and duodenum // World J Gastrointest Pharmacol Ther. - 2019;10(2):35-49. https://doi.org/10.4292/wjgpt.v10.i2.35

63. Yu-Chiao Chiu, Chia-Chang Chen, Chung-Wang Ko, Szu-Chia Liao, Hong-Zen Yeh, Chung-Hsin Chang. Real-world efficacy and safety of vedolizumab among patients with inflammatory bowel disease: A single tertiary medical center experience in Central Taiwan // Adv Dig Med. - 2021;8:40-46. https://doi.org/10.1002/aid2.13188

64. Selvaratnam S., Gullino S., Shim L, Lee E., Lee A., Paramsothy S., Leong R.W. Epidemiology of inflammatory bowel disease in South America: A systematic review // World J Gastroenterol. - 2019;25(47):6866-6875. https://dx.doi.org/10.3748/wjg.v25.i47.6866

65. Shelley-Fraser G., Borley N.R., Warren B.F., Shepherd N. The connective tissue changes of Crohn's disease // Histopathology. - 2012;60(7):1034-1044. https://dx.doi.org/10.1111/j.1365-2559.2011.03911.x.

66. Harbord M. Annese V., Vavricka S.R et al. The First European Evidence-based Consensus on Extra-intestinal Manifestations in Inflammatory Bowel Disease // J Crohns Colitis. - 2016;10(3):239-254. https://doi.org/10.1093/ecco-jcc/jjv213.

67. Vavricka S.R., Manser C.N., Hediger S. et al. Periodontitis and gingivitis in inflammatory bowel disease: a case-control study // Inflamm Bowel Dis. - 2013;19:2768-2777. https://dx.doi.org/10.1097/01.MIB.0000438356.84263.3b

68. Yangyang R.Y., Rodriguez J.R. Clinical presentation of Crohn’s, ulcerative colitis, and indeterminate colitis: Symptoms, extraintestinal manifestations, and disease phenotypes // Seminars in pediatric surgery. - 2017;26:349-355. https://doi.org/10.1053/j.sempedsurg.2017.10.003

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EXTRA-INTESTINAL MANIFESTATIONS OF CROHN DISEASE AND CHRONIC ULCERATIVE COLITIS IN THE ORAL CAVITY

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