Alcoholism as a factor of development and spread of diseases (analytical review)

V. Kurylev; O. A. Uspenskaya; Tatyana Potemina; E. Shevchenko; P. Rudaya

doi:doi:10.12737/7592

Alcoholism as a factor of development and spread of diseases (analytical review)

Published в Journal of New Medical Technologies. eJournal · Volume 9, Issue 1, 2015 · Pages 0–0 · Rubrics: LITERATURE REVIEWS

DOI 10.12737/7592

Received: 26.01.2015 Accepted: 26.01.2015 Published: 26.01.2015 Language of publication: RUS

Authors

V. Kurylev · O. A. Uspenskaya ² · Tatyana Potemina ³ · E. Shevchenko · P. Rudaya

2 Nizhegorodskaya gosudarstvennaya medicinskaya akademiya» Minzdrava Rossii (docent, zaveduyuschaya kafedroy terapevticheskoy stomatologii)
Russian Federation

3 Volga Research Medical University (Department of Pathological Physiology, Professor, head of department)
Nizhniy Novgorod, Nizhny Novgorod, Russian Federation

ABSTRACT

This review presents the modern medical views on the nature of alcoholism and its effect on the development and spread of various diseases. The article characterizes alcoholism pathogenesis on the molecular level, presents the evidence on the disorders of carbohydrate metabolism, immune system, cell death, modulation of mitochondrial permeability and modulation of gene expression due to the alcoholic effect. Alcohol is caracte-rized as a root cause of development and progression of infectious diseases (tuberculosis, pneumonia), cancer, diabetes, nervous system diseases (alcoholic polyneuropathy, Wernicke´s encephalopathy), cardiovascular dis-eases (essential hypertension, ischemic heart disease), hepatic and pancreatic diseases. The review also focuses on the role of the alcohol in the spread of sexually transmitted infections such as syphilis, chlamydial infection, ureaplasma infection, gonorrhea, HIV, herpes simplex, trichomoniasis. The influence of several factors was detected. The first factor relates to the changes occurring in organism as a result of excessive alcohol con-sumption - in particular, to the weakening of the immune system and / or a decrease in the effectiveness of treatment. Another factor dismissed due to antisocial behaviour, often associated with individuals suffering from alcohol dependence

KEYWORDS

alcoholism sexually transmitted infections infectious diseases.

Information References

Authors:

2. Nizhegorodskaya gosudarstvennaya medicinskaya akademiya» Minzdrava Rossii (docent, zaveduyuschaya kafedroy terapevticheskoy stomatologii)

Russian Federation

3. Volga Research Medical University (Department of Pathological Physiology, Professor, head of department)

Nizhniy Novgorod, Nizhny Novgorod, Russian Federation

Type:

Article

Pages:

from 0 to 0

Status:

Published

Language:

Russian

Keywords:

alcoholism, sexually transmitted infections, infectious diseases.

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